Prrx2 - paired related homeobox 2

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; HMG box domain binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including embryonic morphogenesis; positive regulation of mesenchymal cell proliferation; and positive regulation of smoothened signaling pathway. Predicted to be active in nucleus. Orthologous to human PRRX2 (paired related homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]