Abcb7 - ATP-binding cassette, sub-family B (MDR/TAP), member 7

Predicted to enable ABC-type iron-sulfur cluster transporter activity and protein homodimerization activity. Involved in iron-sulfur cluster assembly; positive regulation of heme biosynthetic process; and positive regulation of iron-sulfur cluster assembly. Acts upstream of or within cellular iron ion homeostasis. Located in mitochondrial inner membrane. Is expressed in several structures, including adrenal gland; central nervous system; gut; hemolymphoid system gland; and retina. Human ortholog(s) of this gene implicated in X-linked sideroblastic anemia with ataxia. Orthologous to human ABCB7 (ATP binding cassette subfamily B member 7). [provided by Alliance of Genome Resources, Apr 2022]