Mouse
Aanat - arylalkylamine N-acetyltransferase
Alias:
Nat4
Snat
Nat-2
AA-NAT
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Protein Interaction
Related Models
References
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Models
Reference
3
4
6476 bp
23.07
6
4
Aanat Genetics information (+)
GRCm39
Chr : -
Sequence Homology
Selected Gene:
Mouse:Aanat
Transcripts & Proteins
Table View
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#
Transcript
Length(nt)
Exon count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Expression
Alphabetical
Cell-specific RNA expression
Organ
Expression
Alphabetical
Protein Interaction
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Models
Type
Name
MGI
Strain of Origin
Publications
No data available
References
Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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