Krt5 - keratin 5

Predicted to enable scaffold protein binding activity. Located in keratin filament and plasma membrane. Is expressed in several structures, including alimentary system; epithelium; genitourinary system; integumental system; and sensory organ. Used to study epidermolysis bullosa simplex Dowling-Meara type. Human ortholog(s) of this gene implicated in Dowling-Degos disease; epidermolysis bullosa simplex; and epidermolysis bullosa simplex with mottled pigmentation. Orthologous to human KRT5 (keratin 5). [provided by Alliance of Genome Resources, Apr 2022]