Ampd2 - adenosine monophosphate deaminase 2

Enables AMP deaminase activity. Involved in ATP metabolic process and purine ribonucleotide metabolic process. Acts upstream of or within several processes, including IMP biosynthetic process; cholesterol homeostasis; and energy homeostasis. Predicted to be active in cytosol. Is expressed in several structures, including endocrine gland; genitourinary system; nervous system; and vascular system. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 63 and pontocerebellar hypoplasia type 9. Orthologous to human AMPD2 (adenosine monophosphate deaminase 2). [provided by Alliance of Genome Resources, Apr 2022]