Mouse
Prex2 - phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
Alias:
Depdc2
P-Rex2
D430013K02
6230420N16Rik
C030045D06Rik
Predicted to enable GTPase activator activity and guanyl-nucleotide exchange factor activity. Acts upstream of or within adult locomotory behavior; dendrite morphogenesis; and phosphatidylinositol 3-kinase signaling. Located in plasma membrane. Is expressed in brain ventricular layer and gut. Human ortholog(s) of this gene implicated in Klatskin's tumor. Orthologous to human PREX2 (phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2). [provided by Alliance of Genome Resources, Apr 2022]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Prex2 Genetics information (+)
GRCm39
Chr : -
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
References Literature
Title
PMID
Journal
Year
IF
