Sp110 - Sp110 nuclear body protein

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Acts upstream of or within positive regulation of apoptotic process and response to bacterium. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in genitourinary system and thymus primordium. Human ortholog(s) of this gene implicated in hepatic venoocclusive disease with immunodeficiency and tuberculosis. Orthologous to human SP110 (SP110 nuclear body protein). [provided by Alliance of Genome Resources, Apr 2022]