Fermt3 - fermitin family member 3

Enables integrin binding activity. Involved in several processes, including integrin activation; platelet aggregation; and regulation of cell-cell adhesion mediated by integrin. Located in podosome. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; liver; and lung. Used to study leukocyte adhesion deficiency 3. Human ortholog(s) of this gene implicated in leukocyte adhesion deficiency 1 and leukocyte adhesion deficiency 3. Orthologous to human FERMT3 (FERM domain containing kindlin 3). [provided by Alliance of Genome Resources, Apr 2022]