Baiap2 - brain-specific angiogenesis inhibitor 1-associated protein 2
Alias:
IRSp53
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Predicted to enable several functions, including PDZ domain binding activity; identical protein binding activity; and scaffold protein binding activity. Involved in several processes, including actin filament organization; modification of synaptic structure, modulating synaptic transmission; and regulation of cell shape. Acts upstream of or within dendrite development and regulation of synaptic plasticity. Located in Schaffer collateral - CA1 synapse and neuron projection. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and respiratory system. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome; attention deficit hyperactivity disorder; and autism spectrum disorder. Orthologous to human BAIAP2 (BAR/IMD domain containing adaptor protein 2). [provided by Alliance of Genome Resources, Apr 2022]