Celsr3 - cadherin, EGF LAG seven-pass G-type receptor 3
Alias:
Fmi1
Adgrc3
flamingo
mKIAA0812
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Predicted to enable G protein-coupled receptor activity and calcium ion binding activity. Involved in dopaminergic neuron axon guidance; planar cell polarity pathway involved in axon guidance; and serotonergic neuron axon guidance. Acts upstream of or within several processes, including cilium assembly; generation of neurons; and regulation of protein phosphorylation. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in several structures, including central nervous system; embryo ectoderm; epiblast; peripheral nervous system; and retina. Orthologous to human CELSR3 (cadherin EGF LAG seven-pass G-type receptor 3). [provided by Alliance of Genome Resources, Apr 2022]