Gcm2 - glial cells missing homolog 2

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including cellular response to organic substance; negative regulation of apoptotic process; and parathyroid gland development. Located in nucleus. Is expressed in several structures, including branchial pouch; central nervous system; genitourinary system; gut; and retina. Used to study hypoparathyroidism. Human ortholog(s) of this gene implicated in familial isolated hypoparathyroidism and hyperparathyroidism. Orthologous to human GCM2 (glial cells missing transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]