Ift140 - intraflagellar transport 140

Acts upstream of or within several processes, including cilium organization; embryonic organ development; and nervous system development. Located in cytoskeleton and photoreceptor cell cilium. Part of intraciliary transport particle A. Is expressed in diaphragm; lung; metanephros; and retina. Used to study asphyxiating thoracic dystrophy 1 and short-rib thoracic dysplasia 9 with or without polydactyly. Human ortholog(s) of this gene implicated in retinitis pigmentosa and short-rib thoracic dysplasia 9 with or without polydactyly. Orthologous to human IFT140 (intraflagellar transport 140). [provided by Alliance of Genome Resources, Apr 2022]