Pkdcc - protein kinase domain containing, cytoplasmic
Alias:
Vlk
MAd1
Adtk1
ESTM17
Sgk493
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
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Enables non-membrane spanning protein tyrosine kinase activity. Involved in several processes, including negative regulation of Golgi to plasma membrane protein transport; positive regulation of bone mineralization; and positive regulation of chondrocyte differentiation. Acts upstream of or within bone mineralization; limb morphogenesis; and skeletal system development. Located in Golgi apparatus and extracellular region. Is expressed in several structures, including alimentary system; arm; embryo ectoderm; embryo mesenchyme; and mesothelium. Orthologous to human PKDCC (protein kinase domain containing, cytoplasmic). [provided by Alliance of Genome Resources, Apr 2022]