Enables ubiquitin protein ligase activity. Acts upstream of or within several processes, including glycogen biosynthetic process; proteasome-mediated ubiquitin-dependent protein catabolic process; and regulation of protein modification process. Located in nucleus and perinuclear region of cytoplasm. Used to study Lafora disease. Human ortholog(s) of this gene implicated in Lafora disease. Orthologous to human NHLRC1 (NHL repeat containing E3 ubiquitin protein ligase 1). [provided by Alliance of Genome Resources, Apr 2022]