Fancm - Fanconi anemia, complementation group M

Predicted to enable DNA helicase activity; chromatin binding activity; and four-way junction DNA binding activity. Predicted to be involved in DNA metabolic process and positive regulation of protein monoubiquitination. Predicted to act upstream of or within cellular response to DNA damage stimulus. Predicted to be located in nucleoplasm. Predicted to be part of FANCM-MHF complex and Fanconi anaemia nuclear complex. Is expressed in lung; mandible; and temporal bone petrous part. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 15 and spermatogenic failure 28. Orthologous to human FANCM (FA complementation group M). [provided by Alliance of Genome Resources, Apr 2022]