Isl2 - insulin related protein 2 (islet 2)

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of neuron differentiation and neuron differentiation. Located in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; limb ectoderm; retina; and spinal ganglion. Orthologous to human ISL2 (ISL LIM homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]