Pex12 - peroxisomal biogenesis factor 12

Predicted to enable protein C-terminus binding activity; ubiquitin-protein transferase activity; and zinc ion binding activity. Predicted to be involved in protein import into peroxisome matrix and protein monoubiquitination. Predicted to act upstream of or within protein transport. Predicted to be located in peroxisomal membrane. Predicted to be part of peroxisomal importomer complex. Predicted to be integral component of peroxisomal membrane. Is expressed in esophagus; lung; mandible; and maxilla. Human ortholog(s) of this gene implicated in peroxisomal biogenesis disorder and peroxisome biogenesis disorder 3A. Orthologous to human PEX12 (peroxisomal biogenesis factor 12). [provided by Alliance of Genome Resources, Apr 2022]