Flt3lg - Fms related receptor tyrosine kinase 3 ligand

Predicted to enable identical protein binding activity and receptor tyrosine kinase binding activity. Involved in positive regulation of natural killer cell proliferation. Predicted to be located in cell surface and extracellular space. Predicted to be intrinsic component of external side of plasma membrane. Used to study pancreatic cancer. Human ortholog(s) of this gene implicated in colon carcinoma; glioblastoma; and high grade glioma. Orthologous to human FLT3LG (fms related receptor tyrosine kinase 3 ligand). [provided by Alliance of Genome Resources, Apr 2022]