Chchd10 - coiled-coil-helix-coiled-coil-helix domain containing 10

Involved in several processes, including mitochondria-nucleus signaling pathway; positive regulation of mitochondrial transcription; and stabilization of membrane potential. Located in mitochondrion. Is expressed in several structures, including brain ventricle and choroid plexus; early embryo; hypothalamus mantle layer; renal calyx; and ventral grey horn. Human ortholog(s) of this gene implicated in frontotemporal dementia and/or amyotrophic lateral sclerosis-2. Orthologous to human CHCHD10 (coiled-coil-helix-coiled-coil-helix domain containing 10). [provided by Alliance of Genome Resources, Apr 2022]