Pura - purine rich element binding protein A

Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; nucleic acid binding activity; and transcription regulator inhibitor activity. Predicted to be involved in DNA unwinding involved in DNA replication; dendritic transport of messenger ribonucleoprotein complex; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including epithelial cell proliferation; lymphocyte proliferation; and negative regulation of transcription, DNA-templated. Located in nucleus. Is active in postsynaptic density. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 31. Orthologous to human PURA (purine rich element binding protein A). [provided by Alliance of Genome Resources, Apr 2022]