Vrk3 - vaccinia related kinase 3

Enables protein phosphatase binding activity. Acts upstream of or within negative regulation of ERK1 and ERK2 cascade and positive regulation of phosphoprotein phosphatase activity. Located in nucleus. Is expressed in several structures, including dorsal mesogastrium; hemolymphoid system; liver; metanephros; and yolk sac. Used to study autism spectrum disorder. Orthologous to human VRK3 (VRK serine/threonine kinase 3). [provided by Alliance of Genome Resources, Apr 2022]