Epg5 - ectopic P-granules autophagy protein 5 homolog (C. elegans)

Acts upstream of or within autophagosome maturation and endocytic recycling. Predicted to be located in lysosome and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Used to study amyotrophic lateral sclerosis and retinitis pigmentosa. Human ortholog(s) of this gene implicated in Vici syndrome. Orthologous to human EPG5 (ectopic P-granules autophagy protein 5 homolog). [provided by Alliance of Genome Resources, Apr 2022]