Prdm16 - PR/SET domain 16

Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; histone methyltransferase activity (H3-K9 specific); and transcription coactivator activity. Predicted to be involved in several processes, including brown fat cell differentiation; positive regulation of cold-induced thermogenesis; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of brown fat cell differentiation; and regulation of transcription, DNA-templated. Predicted to be located in aggresome; cytosol; and nucleoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Orthologous to human PRDM16 (PR/SET domain 16). [provided by Alliance of Genome Resources, Apr 2022]