Otulin - OTU deubiquitinase with linear linkage specificity
Alias:
Fam105b
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
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Predicted to enable thiol-dependent deubiquitinase. Predicted to be involved in several processes, including nucleotide-binding activity oligomerization domain containing 2 signaling pathway; protein linear deubiquitination; and regulation of signal transduction. Predicted to be part of LUBAC complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in otulipenia. Orthologous to human OTULIN (OTU deubiquitinase with linear linkage specificity). [provided by Alliance of Genome Resources, Apr 2022]