Adgrv1 - adhesion G protein-coupled receptor V1

Predicted to enable several functions, including G-protein alpha-subunit binding activity; adenylate cyclase inhibitor activity; and calcium ion binding activity. Predicted to be involved in several processes, including negative regulation of adenylate cyclase activity; photoreceptor cell maintenance; and positive regulation of protein kinase C signaling. Predicted to act upstream of or within several processes, including detection of mechanical stimulus involved in sensory perception of sound; inner ear receptor cell stereocilium organization; and positive regulation of protein kinase A signaling. Located in stereocilium and synapse. Human ortholog(s) of this gene implicated in Usher syndrome type 2C and familial febrile seizures 4. Orthologous to human ADGRV1 (adhesion G protein-coupled receptor V1). [provided by Alliance of Genome Resources, Apr 2022]