H3f3a - H3.3 histone A

Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; RNA polymerase II core promoter sequence-specific DNA binding activity; and nucleosomal DNA binding activity. Predicted to be involved in DNA replication-independent chromatin assembly; nucleosome assembly; and positive regulation of cell growth. Predicted to act upstream of or within several processes, including gamete generation; heterochromatin organization; and negative regulation of chromosome condensation. Predicted to be located in Barr body and chromosome, telomeric region. Predicted to be part of nucleosome. Orthologous to several human genes including H3-3B (H3.3 histone B). [provided by Alliance of Genome Resources, Apr 2022]