Predicted to enable PDZ domain binding activity. Predicted to be involved in regulation of postsynaptic neurotransmitter receptor activity and regulation of short-term neuronal synaptic plasticity. Predicted to act upstream of or within regulation of AMPA receptor activity. Predicted to be located in dendritic spine membrane; postsynaptic density; and postsynaptic membrane. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in glutamatergic synapse. Predicted to be integral component of postsynaptic density membrane. Orthologous to human SHISA9 (shisa family member 9). [provided by Alliance of Genome Resources, Apr 2022]