Enables several functions, including NADP binding activity; carboxylic acid binding activity; and phosphogluconate dehydrogenase (decarboxylating) activity. Involved in D-gluconate metabolic process and pentose-phosphate shunt, oxidative branch. Located in intracellular membrane-bounded organelle. Orthologous to human PGD (phosphogluconate dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]