Kdm5d - lysine demethylase 5D

Predicted to enable androgen receptor binding activity and histone H3-tri/di/monomethyl-lysine-4 demethylase activity. Predicted to be involved in chromatin remodeling and regulation of androgen receptor signaling pathway. Predicted to act upstream of or within T cell antigen processing and presentation and histone H3-K4 demethylation. Predicted to be located in fibrillar center. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Claes-Jensen type. Orthologous to several human genes including KDM5D (lysine demethylase 5D). [provided by Alliance of Genome Resources, Apr 2022]