Enables alcohol dehydrogenase (NAD+) activity. Involved in aging and ethanol catabolic process. Located in cytoplasm and nucleus. Used to study alcohol use disorder. Biomarker of cholestasis. Human ortholog(s) of this gene implicated in AMED syndrome and asthma. Orthologous to human ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide). [provided by Alliance of Genome Resources, Apr 2022]