Hsd3b8 - hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 8

Predicted to enable 3-beta-hydroxy-delta5-steroid dehydrogenase activity and steroid delta-isomerase activity. Predicted to be located in several cellular components, including intercellular bridge; mitochondrial envelope; and nucleolus. Is expressed in several structures, including alimentary system; eye; heart; integumental system; and nervous system. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2). [provided by Alliance of Genome Resources, Apr 2022]