Ldlrap1 - low density lipoprotein receptor adaptor protein 1

Enables amyloid-beta binding activity. Acts upstream of or within cholesterol homeostasis. Located in early endosome and neurofilament. Is expressed in naris; nasal cavity respiratory epithelium; olfactory epithelium; parietal endoderm; and yolk sac endoderm. Used to study autosomal recessive hypercholesterolemia. Human ortholog(s) of this gene implicated in autosomal recessive hypercholesterolemia. Orthologous to human LDLRAP1 (low density lipoprotein receptor adaptor protein 1). [provided by Alliance of Genome Resources, Apr 2022]