Zollinger-Ellison Syndrome, also known as gastrinoma, is related to hyperparathyroidism and esophagitis, and has symptoms including dyspepsia An important gene associated with Zollinger-Ellison Syndrome is GAST (Gastrin), and among its related pathways/superpathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signalling. The drugs Dexlansoprazole and Lansoprazole have been mentioned in the context of this disorder. Affiliated tissues include pancreas and small intestine, and related phenotypes are neuroendocrine neoplasm and zollinger-ellison syndrome