Xeroderma Pigmentosum Group E (XP5)

Xeroderma Pigmentosum Group E, also known as xeroderma pigmentosum, group e, is related to xeroderma pigmentosum, complementation group e and xeroderma pigmentosum, complementation group a. An important gene associated with Xeroderma Pigmentosum Group E is DDB2 (Damage Specific DNA Binding Protein 2), and among its related pathways/superpathways are Class I MHC mediated antigen processing and presentation and Transcription-Coupled Nucleotide Excision Repair (TC-NER). Affiliated tissues include skin and colon, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Increased S length, increased G2 length