Xeroderma Pigmentosum, Complementation Group E (XP-E)

Xeroderma Pigmentosum, Complementation Group E, also known as xeroderma pigmentosum, group e, ddb-negative subtype, is related to xeroderma pigmentosum group e and xeroderma pigmentosum, variant type. An important gene associated with Xeroderma Pigmentosum, Complementation Group E is DDB2 (Damage Specific DNA Binding Protein 2), and among its related pathways/superpathways are Metabolism of proteins and Class I MHC mediated antigen processing and presentation. Affiliated tissues include skin and brain, and related phenotypes are photophobia and melanoma