Witkop Syndrome (ECTD3)

Alias:

Tooth and Nail Syndrome

Hypoplastic Enamel-Onycholysis-Hypohidrosis Syndrome

Ectodermal Dysplasia 3, Tooth/nail Type

Hypodontia-Dysplasia of Nails Syndrome

Ectodermal Dysplasia 3, Witkop Type

Hypodontia-Nail Dysgenesis Syndrome

Tooth-and-Nail Syndrome

Ectd3

Tns

Dysplasia of Nails with Hypodontia

Nail Dysplasia with Hypodontia

Dysplasia, Ectodermal, Type 3

Hypodontia-Nail Dysgenesis

Witkop's Syndrome

Favorite

Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Witkop Syndrome, also known as tooth and nail syndrome, is related to ectodermal dysplasia 8, hair/tooth/nail type and tooth agenesis, and has symptoms including koilonychia An important gene associated with Witkop Syndrome is MSX1 (Msh Homeobox 1), and among its related pathways/superpathways are Signaling by WNT and ncRNAs involved in Wnt signaling in hepatocellular carcinoma. Affiliated tissues include skin and bone, and related phenotypes are abnormality of the dentition and abnormality of the nail

Related ID：

MALACARDS：WTK002

OMIM：189500

MESH：C536736