Wrinkly Skin Syndrome (WSS)

Wrinkly Skin Syndrome, also known as wss, is related to cutis laxa, autosomal recessive, type iib and immunodeficiency 47. An important gene associated with Wrinkly Skin Syndrome is ATP6V0A2 (ATPase H+ Transporting V0 Subunit A2), and among its related pathways/superpathways are Keratinization and Amino acid metabolism. Affiliated tissues include skin and bone, and related phenotypes are excessive skin wrinkling on dorsum of hands and fingers and failure to thrive