Wernicke-Korsakoff Syndrome, also known as korsakoff syndrome, is related to wernicke encephalopathy and amnestic disorder, and has symptoms including ataxia and ophthalmoplegia. An important gene associated with Wernicke-Korsakoff Syndrome is TKT (Transketolase), and among its related pathways/superpathways are Metabolism and Metabolism of water-soluble vitamins and cofactors. The drugs Thiamine and Folic acid have been mentioned in the context of this disorder. Affiliated tissues include thalamus and hypothalamus, and related phenotypes are ptosis and ataxia