Wilson Disease (WND)

Alias:
Hepatolenticular Degeneration
Wilson's Disease
Wd
Westphal-Strumpell Syndrome
Copper Storage Disease
Progressive Hepatolenticular Degeneration
Hepatolenticular Degeneration Syndrome
Lenticular Degenerative Disease
Hepatocerebral Degeneration
Neurohepatic Degeneration
Cerebral Pseudosclerosis
Westphal Pseudosclerosis
Kinnier-Wilson Disease
Lenticular Syndrome
Wilson's Syndrome
Copper Retention
Wnd
Favorite
Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Wilson Disease, also known as hepatolenticular degeneration, is related to liver disease and disorder of copper metabolism, and has symptoms including abdominal pain, back pain and constipation. An important gene associated with Wilson Disease is ATP7B (ATPase Copper Transporting Beta), and among its related pathways/superpathways are Detoxification of Reactive Oxygen Species and Amyotrophic lateral sclerosis (ALS). The drugs Zinc cation and Copper have been mentioned in the context of this disorder. Affiliated tissues include Liver and eye, and related phenotypes are intellectual disability and failure to thrive
Related ID:
MESH:D006527
ICD11:468161208

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AR
Child
1-5/10000
49
741
514

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

#
Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top