Wilms Tumor 1 (WT1)

Alias:
Nephroblastoma
Wilms Tumor
Renal Embryonic Tumor
Wilms' Tumor
Wt1
Nonanaplastic Kidney Wilms Tumor
Wilms Tumor, Type 1, Somatic
Childhood Kidney Wilms Tumor
Adult Kidney Wilms Tumor
Bilateral Wilms Tumor
Wilms Tumor, Somatic
Adult Nephroblastoma
Wilms Tumor, Type 1
Wt1 Disorder
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Wilms Tumor 1, also known as nephroblastoma, is related to wilms tumor 5 and nephrotic syndrome, type 4, and has symptoms including abdominal pain An important gene associated with Wilms Tumor 1 is WT1 (WT1 Transcription Factor), and among its related pathways/superpathways are DNA IR-double strand breaks and cellular response via ATM and DNA IR-damage and cellular response via ATR. The drugs Itraconazole and Vincristine have been mentioned in the context of this disorder. Affiliated tissues include kidney and t cells, and related phenotypes are abdominal pain and neoplasm
Related ID:

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AD
Child
1-9/1000000
174
2483
214

Medical Symptom

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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
Journal
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IF
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