Wolman Disease (WOLD)

Wolman Disease, also known as wolman's disease, is related to cholesteryl ester storage disease and hypercholesterolemia, familial, 1, and has symptoms including diarrhea and vomiting. An important gene associated with Wolman Disease is LIPA (Lipase A, Lysosomal Acid Type), and among its related pathways/superpathways are Metabolism and Transport of inorganic cations/anions and amino acids/oligopeptides. The drugs Cyclophosphamide and Busulfan have been mentioned in the context of this disorder. Affiliated tissues include liver and spleen, and related phenotypes are nausea and vomiting and global developmental delay