Wolfram Syndrome 2 (WFS2)

Wolfram Syndrome 2, also known as wfs2, is related to wolfram syndrome and 3-methylglutaconic aciduria, type iii. An important gene associated with Wolfram Syndrome 2 is CISD2 (CDGSH Iron Sulfur Domain 2), and among its related pathways/superpathways are Immune response Function of MEF2 in T lymphocytes and Glucose / Energy Metabolism. The drugs Acetylcysteine and Deferiprone have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and bone, and related phenotypes are gastric ulcer and depression