Vitreoretinopathy, Neovascular Inflammatory (VRNI)

Alias:
Proliferative Vitreoretinopathy
Adniv
Autosomal Dominant Neovascular Inflammatory Vitreoretinopathy
Neovascular Inflammatory Vitreoretinopathy
Vrni
Pvr
Vitreoretinopathy, Neovascular Inflammatory, Autosomal Dominant
Neovascular Inflammatory Vitreoretinopathy Autosomal Dominant
Vitreoretinopathy, Proliferative
Proliferative Vitreo-Retinopathy
Vitreoretinopathy Proliferative
Retinitis Proliferans
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Vitreoretinopathy, Neovascular Inflammatory, also known as proliferative vitreoretinopathy, is related to retinal detachment and pulmonary hypertension. An important gene associated with Vitreoretinopathy, Neovascular Inflammatory is CAPN5 (Calpain 5), and among its related pathways/superpathways are Apoptotic Pathways in Synovial Fibroblasts and ERK Signaling. The drugs Triamcinolone and Bupivacaine have been mentioned in the context of this disorder. Affiliated tissues include eye and retina, and related phenotypes are blindness and abnormal electroretinogram
Related ID:

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AD
All ages
<1/1000000
25
262
6

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
Journal
Year
IF
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