Vitamin K-Dependent Clotting Factors, Combined Deficiency of, 2 (VKCFD2)

Vitamin K-Dependent Clotting Factors, Combined Deficiency of, 2, also known as vitamin k-dependent clotting factors, combined deficiency of, type 2, is related to vitamin k deficiency bleeding and rare hemorrhagic disorder. An important gene associated with Vitamin K-Dependent Clotting Factors, Combined Deficiency of, 2 is VKORC1 (Vitamin K Epoxide Reductase Complex Subunit 1), and among its related pathways/superpathways are Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation and Vitamin K metabolism and activation of dependent proteins. Affiliated tissues include bone marrow and liver, and related phenotypes are abnormal bleeding and reduced factor x activity