Vitamin K-Dependent Clotting Factors, Combined Deficiency of, 1 (VKCFD1)

Alias:

Vitamin K-Dependent Clotting Factors, Combined Deficiency of, Type 1

Combined Deficiency of Vitamin K-Dependent Clotting Factors 1

Vkcfd1

Multiple Coagulation Factor Deficiency Iii

Vitamin K-Dependent Coagulation Defect

Mcfd3

Familial Multiple Coagulation Factor Deficiency Iii

Factors Ii, Vii, Ix, and X, Combined Deficiency of

Glutamic Acid, Deficient Gamma-Carboxylation of

Fmfd Iii

Vkcfd

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Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Vitamin K-Dependent Clotting Factors, Combined Deficiency of, 1, also known as vitamin k-dependent clotting factors, combined deficiency of, type 1, is related to vitamin k-dependent clotting factors, combined deficiency of, 2 and hereditary combined deficiency of vitamin k-dependent clotting factors. An important gene associated with Vitamin K-Dependent Clotting Factors, Combined Deficiency of, 1 is GGCX (Gamma-Glutamyl Carboxylase), and among its related pathways/superpathways are Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation and Vitamin K metabolism and activation of dependent proteins. Affiliated tissues include liver and bone marrow, and related phenotypes are prolonged prothrombin time and reduced factor x activity

Related ID：

MALACARDS：VTM009

OMIM：277450

MESH：C564741