Vascular Malformation, Primary Intraosseous, also known as primary intraosseous venous malformation, is related to hemangioma and cavernous hemangioma, and has symptoms including unspecified visual loss An important gene associated with Vascular Malformation, Primary Intraosseous is ELMO2 (Engulfment And Cell Motility 2). Affiliated tissues include bone and thyroid, and related phenotypes are facial asymmetry and gingival bleeding