Varicocele, also known as scrotal varices, is related to varicose veins and male infertility, and has symptoms including pain in scrotum An important gene associated with Varicocele is GNRH1 (Gonadotropin Releasing Hormone 1), and among its related pathways/superpathways are Host-pathogen interaction of human coronaviruses - apoptosis and Nongenotropic Androgen signaling. The drugs Methylene blue and Bupivacaine have been mentioned in the context of this disorder. Affiliated tissues include testis and heart, and related phenotype is reproductive system.