Von Hippel-Lindau Syndrome (VHLS)

Von Hippel-Lindau Syndrome, also known as von hippel-lindau disease, is related to hemangioblastoma and pancreatic serous cystadenoma, and has symptoms including tinnitus and vertigo. An important gene associated with Von Hippel-Lindau Syndrome is VHL (Von Hippel-Lindau Tumor Suppressor), and among its related pathways/superpathways are Signal Transduction and GDNF signaling. The drugs Somatostatin and Ranibizumab have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and pancreas, and related phenotypes are abnormality of the eye and hypertension