Vein Disease, also known as disorder of vein, is related to venous insufficiency and varicose veins, and has symptoms including vein pain An important gene associated with Vein Disease is F2 (Coagulation Factor II, Thrombin), and among its related pathways/superpathways are Signal Transduction and Response to elevated platelet cytosolic Ca2+. The drugs Ethanol and Heparin, bovine have been mentioned in the context of this disorder. Affiliated tissues include skin and neutrophil, and related phenotypes are homeostasis/metabolism and nervous system