Von Economo's Disease, also known as encephalitis lethargica, is related to viral encephalitis and akinetic mutism. An important gene associated with Von Economo's Disease is HCRT (Hypocretin Neuropeptide Precursor), and among its related pathways/superpathways are Neuroscience and Parkinson's disease pathway. Affiliated tissues include eye and brain, and related phenotypes are encephalopathy and sleep abnormality